Do-Coop Technologies has considered the unique properties of water and physical principles to invent patented water-based nanotechnology, branded as Neowater, a revolutionary solution for drug development and drug delivery challenges. The proprietary process in which Neowater is created includes insoluble crystals which are heated to 900°C and dropped into an irradiated chamber of ultra-pure water that is kept below the anomaly temperature. The consequence is a "Nano Bang" which causes a homogenous distribution of the nanoparticles, 5-50 nm in diameter, and an elevated amount of insoluble inorganic carbon dioxide (IC), up to 100-fold more than natural water.
The unique organization of the water molecules in Neowater is derived from interaction with carbon dioxide and a suspended minute amount of insoluble nanoparticles, ten to the fifteenth power of particles per liter.
Neowater harnesses the surface effect produced by these insoluble nanoparticles and carbon dioxide, to create structure within the water and thereby reduce the entropy of the bulk. In addition to the high concentration of IC, 0.5 ppm to 100 ppm, Neowater is characterized by a pH in the range of 6-8 and a conductivity-based IC (1ppm IC= 22 µs/cm). All unique characteristics of Neowater can be controlled during the proprietary production process.
Neowater results not only in new and better formulation of hydrophobic and hydrophilic drugs, but also higher stability of proteins and cell cultures, the enhancement of biological in-vitro and in-vivo reactions, and a reduced need for the introduction of stabilizers, detergents, co-solvents or surfactants.
Do-Coop submitted a DMF file for Neowater to the US Food and Drug Administration (DMF# 20503). Its DMF file includes all the toxic studies requested by the FDA, proving that it is a non-toxic safe to use material. Neowater is manufactured under cGMP conditions.